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. 2022 Oct 28;10:1009775. doi: 10.3389/fpubh.2022.1009775

Table 4.

Effects of exercise on cognition using fixed effects linear regression by cognitive group.

MMSE Normal MCI Dementia
Coefficient Std. err. t P > |t| [95% conf. interval] Coefficient Std. err. t P > |t| [95% conf. interval] Coefficient Std. err. t P > |t| [95% conf. interval]
Sex −0.039 0.019 −2.05 0.04* −0.075 −0.002 −0.241 0.055 −4.35 <0.001*** −0.350 −0.133 −0.208 0.147 −1.42 0.155 −0.496 0.079
Education 0.378 0.028 13.27 <0.001*** 0.322 0.434 0.141 0.089 1.58 0.114 −0.034 0.315 0.169 0.252 0.67 0.504 −0.326 0.663
Age −0.032 0.003 −10.29 <0.001*** −0.038 −0.026 −0.175 0.009 −18.98 <0.001*** −0.194 −0.157 −0.188 0.023 −8.1 <0.001*** −0.233 −0.143
Marital state −0.053 0.070 −0.76 0.447 −0.191 0.084 0.273 0.179 1.52 0.128 −0.078 0.624 1.260 0.456 2.76 0.006** 0.367 2.154
Social contact 0.015 0.013 1.2 0.229 −0.010 0.040 0.214 0.034 6.23 <0.001*** 0.147 0.281 0.435 0.090 4.83 <0.001*** 0.259 0.612
Smoking 0.094 0.044 2.14 0.032 0.008 0.180 −0.018 0.132 −0.14 0.890 −0.277 0.240 0.126 0.363 0.35 0.729 −0.586 0.838
Alcohol assumption −0.002 0.032 −0.07 0.945 −0.064 0.060 −0.038 0.097 −0.39 0.698 −0.228 0.152 0.029 0.281 0.1 0.918 −0.521 0.579
Depression −0.119 0.012 −9.58 <0.001*** −0.143 −0.095 −0.179 0.032 −5.6 <0.001*** −0.242 −0.116 −0.260 0.077 −3.36 0.001** −0.412 −0.108
ADL −0.562 0.076 −7.36 <0.001*** −0.712 −0.412 −0.326 0.170 −1.92 0.057 −0.663 0.010 −0.084 0.173 −0.48 0.629 −0.424 0.256
IADL −0.172 0.031 −5.5 <0.001*** −0.234 −0.111 −0.355 0.065 −5.46 <0.001*** −0.482 −0.228 −1.227 0.085 −14.47 <0.001*** −1.393 −1.061
Personal allowance (USD) 0.000 0.001 <0.001 0.996 −0.002 0.002 −0.006 0.005 −1.17 0.240 −0.015 0.004 −0.024 0.020 −1.2 0.231 −0.063 0.015
Exercise sufficiency (reference: no exercise) 0.083 0.047 1.78 0.075 −0.008 0.175 0.183 0.173 1.06 0.290 −0.156 0.522 2.914 0.608 4.79 <0.001*** 1.723 4.105
0.048 0.047 1.02 0.307 −0.044 0.141 0.376 0.158 2.39 0.017* 0.067 0.686 2.803 0.450 6.23 <0.001*** 1.921 3.685
Constant 29.325 0.300 97.89 <0.001*** 28.737 29.912 36.510 0.913 39.99 <0.001*** 34.721 38.299 33.958 2.369 14.33 <0.001*** 29.315 38.602
F (p-value) 403.09 (<0.001***) 467.07 (<0.001***) 72.17 (<0.001***)

***p < 0.001, **p < 0.01, *p < 0.05.