Table 3.
Modified Valent Response Criteria*.
| Response** | Subcategory*** | MC infiltrate in organ | Tryptase level | Organomegaly | C-Finding(s) (CF) |
|---|---|---|---|---|---|
| MR | CR | disappeared [and] ↓< 20 ng/ml [and] disappeared | ≥ 1 CF resolved; and no CF↑ | ||
| IR | decrease [and/or] ↓> 50% [and/or] ↓> 50% | ≥ 1 CF resolved; and no CF ↑ | |||
| PCR | no significant change | ↓ ≤ 50% – 0% | no significant change | ≥ 1 CF resolved; and no CF ↑ | |
| PR | GPR | N/A | N/A | no significant change | ≥ 1 CF ↓by > 50%; no CF ↑ |
| MinR | unchanged | unchanged | no significant change | ≥ 1 CF↓ by > 20% – ≤ 50%; no CF ↑ | |
| NR | SD | unchanged | unchanged | unchanged | CFs ti by +/− 0–20% |
| PD | unchanged or worsened | unchanged or worsened | unchanged or worsened | ≥ 1 CF ↑by > 20% | |
*
Derived from ref. 23.
**
MR: Major Response; PR: Partial Response; NR: No Response.
***
CR: Complete Remission; IR: Incomplete
Remission; PCR: Pure Clinical Response; GPR: Good Partial Response; MinR: Minor Response; SD: Stable Disease; PD: Progressive Disease. ≥ 1 CF: more than one C-Finding … ↓: decrease/regression [to …] ↑: increase/progression [to …].