eAPPENDIX.

Calculations for Determining Direct Cost Savings

Cost of requested therapy

Cost of requested therapy = (daily drug acquisition cost) × (duration of therapy)

Cost of recommended alternative therapy

Cost of recommended alternative therapy = (daily drug acquisition cost) × (duration of therapy)

Duration of therapy was annualized or as stated if < 1 year

Cost of review for all CC PADRs

Cost of review for all CC PADRs = (cost per PADR) × (total PADRs)

Cost per PADR = (average time to completion) × (salary plus benefits)

Direct cost savings

Direct cost savings = (sum of requested therapies for CC PADR nonapprovals) – (sum of recommended alternative therapies for CC PADR nonapprovals) − (cost of review for all CC PADRs)

Abbreviations: CC, community care; PADR, prior authorization drug request.