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. 2022 Jun 16;31(22):3789–3806. doi: 10.1093/hmg/ddac132

Table 1.

Five-level severity scale used to classify SCOURGE patients

Level Clinical findings
Severity 0 (asymptomatic) Asymptomatic
Severity 1 (mild) With symptoms, but without pulmonary infiltrates or need of oxygen therapy
Severity 2 (moderate) With pulmonary infiltrates affecting <50% of the lungs or need of supplemental oxygen therapy
Severity 3 (severe) Hospitalized with any of the following criteria:
 

  • PaO2 < 65 mmHg or SaO2 < 90%

  • PaO2/FiO2 < 300

  • SaO2/FiO2 < 440

  • Dyspnea

  • Respiratory frequency ≥ 22 bpm

  • Infiltrates affecting > 50% of the lungs
Severity 4 (critical) Admission to the ICU or need of mechanical ventilation (invasive or non-invasive)

Note: PaO2, partial pressure of oxygen in arterial blood; SaO2, saturation of oxygen in arterial blood; FiO2, fraction of inspired oxygen.