Table 2.

Comparison between patients with and without flares regarding monthly serum urate (SU) change exceeding thresholds

Month(s)		N	Mean SU change	p-value	SU change, > 30 µmol/L (%)	p-value, flare vs. no flare	SU change, > 60 µmol/L (%)	p-value, flare vs. no flare	SU change, > 90 µmol/L (%)	p-value, flare vs. no flare
0–1	Flare +	37	102	0.16	81.1	0.64	62.2	0.76	48.6	0.41
	Flare −	165	82		77.6		64.8		41.2
1–2	Flare +	25	25	0.06	48.0	0.30	32.0	0.31	24.0	0.89
	Flare −	166	47		49.0		42.8		25.3
2–3	Flare +	28	27	0.40	46.4	0.86	28.6	0.94	10.7	0.47
	Flare −	150	30		47.7		29.3		16.0
3–4	Flare +	41	3	0.28	29.3	0.35	14.6	0.32	25.0	0.93
	Flare −	129	11		37.2		21.7		75.0
4–5	Flare +	14	24	0.24	50.0	0.90	28.6	0.97	7.1	0.28
	Flare −	52	35		48.1		30.8		19.2
5–6	Flare +	21	23	0.034	38.1	0.12	23.8	0.22	14.3	0.13
	Flare −	49	− 7		20.4		12.2		4.1
6–7	Flare +	14	42	0.08	57.1	0.09	35.7	0.22	21.4	0.14
	Flare −	41	13		31.7		19.5		7.3
7–8	Flare +	6	33	0.15	50.0	0.51	33.3	0.07	0	0.64
	Flare −	28	− 4		35.7		7.1		3.6
8–9	Flare +	4	− 18	0.30	25.0	0.63	25.0	0.77	0	0.34
	Flare −	32	5		37.5		18.8		18.8
9–10	Flare +	13	56	0.19	61.5	0.16	38.5	0.60	38.5	0.26
	Flare −	36	30		38.9		30.6		22.2
10–11	Flare +	4	− 38	0.14	25.0	0.56	0	0.29	0	0.59
	Flare −	22	12		13.6		22.7		13
11–12	Flare +	8	6	0.46	25.0	0.61	0	0.71	0	ND
	Flare −	20	7		15.0		5.0		0
Period
0–3	Flare +	59	141	0.046	88.1	0.07	83.1	0.08	67.8	0.051
	Flare −	139	165		95.5		91.5		80.8
3–6	Flare +	85	19	0.44	38.8	0.94	28.2	0.57	10.6	0.39
	Flare −	94	17		39.4		24.5		14.9
6–9	Flare +	47	10	0.10	49.0	0.005	25.5	0.11	25.5	0.13
	Flare −	110	26		26.5		15.5		15.5
9–12	Flare +	59	4	0.34	32.2	0.18	16.9	0.16	11.9	0.24
	Flare −	104	9		22.6		9.4		6.6
12–24	Flare +	41	− 1	0.15	24.4	0.86	11.1	0.91	6.7	0.70
	Flare −	113	11		25.8		11.7		4.7

P-value with independent t-test or chi-squared/Fisher exact test for comparisons flare versus no flare

ND, not determinable