Table 6.

Short term effect of high-salt (4% in chow) diet followed by amoxicillin treatment on the mean relative abundance of major bacterial groups at family level in mice.

Family	Relative abundance (%)				Significance (Adjusted p-value)
	CD	CD + A	HSD	HSD. + A	CD versus CD + A	CD versus HSD	HSD versus HSD + A
Lactobacillaceae	4.50 ± 0.207	0.1 ± 0.031	8.50 ± 0.278	0.30 ± 0.054	< 0.0001	< 0.0001	< 0.0001
Clostridiaceae	5.90 ± 0.235	0.1 ± 0.031	2.10 ± 0.143	0.20 ± 0.044	< 0.0001	< 0.0001	< 0.0001
Lachnospiraceae	12.40 ± 0.329	0.4 ± 0.063	11.80 ± 0.322	1.30 ± 0.113	< 0.0001	< 0.0001	< 0.0001
Ruminococcaceae	17.40 ± 0.379	0.2 ± 0.044	2.70 ± 0.162	0.40 ± 0.063	< 0.0001	< 0.0001	< 0.0001
Erysipelotrichaceae	0.30 ± 0.063	0.1 ± 0.031	5.20 ± 0.222	0.50 ± 0.070	< 0.0001	< 0.0001	< 0.0001
Desulfovibrionaceae	3.00 ± 0.170	0.2 ± 0.044	6.80 ± 0.251	0.30 ± 0.054	< 0.0001	< 0.0001	< 0.0001
Enterobacteriaceae	0.70 ± 0.083	47.3 ± 0.499	1.00 ± 0.099	56.8 ± 0.495	< 0.0001	NS	< 0.0001
Bacteroidaceae	0.20 ± 0.044	26.7 ± 0.442	0.20 ± 0.044	3.60 ± 0.186	< 0.0001	NS	< 0.0001
S24-7	4.10 ± 0.198	4.9 ± 0.215	1.00 ± 0.099	0.80 ± 0.089	< 0.0001	< 0.0001	NS
Coriobacteriaceae	1.40 ± 0.117	0.2 ± 0.044	5.10 ± 0.219	0.50 ± 0.070	< 0.0001	< 0.0001	< 0.0001
Verrucomicrobiaceae	0.10 ± 0.031	0.10 ± 0.031	6.40 ± 0.244	7.90 ± 0.269	NS	< 0.0001	< 0.0001
F16	0.10 ± 0.031	0.10 ± 0.031	11.60 ± 0.320	0.10 ± 0.031	NS	< 0.0001	< 0.0001

Values are expressed as the means ± SD. Data were analyzed by one-way ANOVA, followed by Bonferroni test, n = 6, p ≤ 0.05, NS = Not significant, CD: Standard—chow diet for 3 weeks; CD + A.: Standard—chow diet for 3 weeks and underwent Amoxicillin treatment in 3rd week; HSD: High-salt diet for 3 weeks; HSD + A.: High-salt diet for 3 weeks and underwent Amoxicillin treatment in 3rd week.