Fig. 8. Differential compartment analysis of pseudo-bulk single-cell Hi-C data from post-natal mouse brain development.

A Single-cell Hi-C summary and our categorization of 6 time points from each mouse brain region into three groups, namely – Early (includes Day 1, 7), Mid (Day 28, 56), and Late (Day 309, 347). B, C The transition of differential compartments in Early, Mid and Late groups within cortex and hippocampal region. D, E Time-series clustering of differential compartments in cortex and the functional enrichment of genes overlapping with these compartments. F, G Time-series clustering of differential compartments in hippocampus and the functional enrichment of genes overlapping with the compartments. H, I Example genes overlapping differential compartments from cortex and hippocampus. Source data are provided as a Source Data file.