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. 2022 Oct;10(20):1092. doi: 10.21037/atm-22-1206

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2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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BMSCs improve the histological changes of the aging mice. (A-D) Images of H&E and Masson trichromatic staining of skin (A), bladder (B), liver (C) and lung (D) of control, aged and BMSCs-treated aged mice. (E) The determination of MDA content in bladder, liver, skin, heart, spleen, lung, kidney and pancreas of control, aging and aging BMSCs treatment groups. Scale bar: 200 µm. Data were expressed as mean ± SE and analyzed using one-way ANOVA. n=6, *, P<0.05, **, P<0.01, and ***, P<0.001. H&E, hematoxylin & eosin; BMSCs, bone marrow-derived mesenchymal stem cells; MDA, malondialdehyde; SE, standard error.