Table 3. A total of 14 major components that acted on hemostasis-related hub targets.
| No. | Compound | Formula | MW | OB (%) | DL | Count | Target |
|---|---|---|---|---|---|---|---|
| F5 | Genistein | C15H10O5 | 270.24 | 17.93 | 0.21 | 15 | AKT1, CDKN1A, EGFR, ESR1, HIF1A, IL6, MAPK1, MAPK14, RELA, STAT1, STAT3, TGFB1, TNF, TP53, VEGFA |
| F6 | Quercetin | C15H10O7 | 302.25 | 46.43 | 0.28 | 15 | AKT1, CDKN1A, EGFR, HIF1A, IL6, JUN, MAPK1, PIK3R1, RELA, SRC, STAT1, TGFB1, TNF, TP53, VEGFA |
| T2 | Ursolic acid | C30H48O3 | 456.78 | 16.77 | 0.75 | 8 | CDKN1A, CREB1, IL6, RELA, STAT3, TNF, TP53, VEGFA |
| F7 | Kaempferol | C15H10O6 | 286.25 | 41.88 | 0.24 | 4 | AKT1, RELA, STAT1, TNF |
| P12 | Paeonol | C9H10O3 | 166.19 | 28.79 | 0.04 | 4 | AKT1, MAPK1, RELA, TNF |
| F1 | Rutin | C27H30O16 | 610.57 | 3.2 | 0.68 | 3 | IL6, RELA, TNF |
| P42 | Lauric acid | C12H24O2 | 200.36 | 23.59 | 0.04 | 3 | AKT1, IL6, RELA |
| F10 | Chrysin | C15H10O4 | 254.25 | 22.61 | 0.18 | 2 | CDKN1A, TGFB1 |
| F11 | Corymbosin | C19H18O7 | 358.37 | 51.96 | 0.41 | 2 | ESR1, MAPK14 |
| T9 | Beta-sitosterol | C29H50O | 414.79 | 36.91 | 0.75 | 1 | TGFB1 |
| F8 | 3-Methylkempferol | C16H12O6 | 300.28 | 60.16 | 0.26 | 1 | MAPK14 |
| P1 | Caffeic acid | C9H8O4 | 180.17 | 25.76 | 0.05 | 1 | TNF |
| O6 | Hexanal | C6H12O | 100.18 | 55.71 | 0.01 | 1 | TNF |
| O12 | Farnesol | C15H26O | 222.41 | 28.44 | 0.06 | 1 | IL6 |
MW, molecular weight; OB, oral bioavailability; DL, drug-likeness.