Table 3. Clinical characteristics of SMPP in children and adults.
| Characteristics | Children (n=281) | Adults (n=20) | P value |
|---|---|---|---|
| Clinical presentation (n, %) | |||
| Common symptoms | 281/281 (100.00) | 20/20 (100.00) | 1.0000 |
| Extrapulmonary symptoms | 116/281 (41.28) | 3/20 (15.00) | 0.0306 |
| Laboratory detection (range) | |||
| White blood cells (×109/L) | 6.3 (2.8–16.4) | 7.9 (3.9–20.1) | 0.1026 |
| Neutrophil rate (%) | 62.8 (22.4–81.7) | 65.4 (30.2–87.2) | 0.3801 |
| Lymphocyte rate (%) | 28.8 (9.5–65.0) | 31.0 (8.1–60.4) | 0.4661 |
| C-reactive protein (mg/L) | 125.4 (27.1–237.3) | 66.3 (10.2–125.6) | <0.0001 |
| LDH (U/L) | 447 [150–1,129] | 309 [170–620] | 0.0032 |
| Imaging manifestations (n, %) | |||
| Unilobar infiltration | 83/281 (29.54) | 12/20 (60.00) | 0.0105 |
| Multilobar infiltrates | 198/281 (70.46) | 8/20 (40.00) | 0.0105 |
| Pleural effusion | 115/281 (40.63) | 6/20 (30.00) | 0.4797 |
Common symptoms: cough, sputum, headache, sore throat, fever, malaise, chest pain, tachypnea; extrapulmonary symptoms: skin rash, meningitis, myocarditis, hemolytic anemia, myalgia, digestive symptoms, hemolytic anemia and nephritis. SMPP, severe Mycoplasma pneumoniae pneumonia; LDH, lactate dehydrogenase.