FIG. 1.

(A) Mouse body weight change after chlamydial challenge infection. Groups of mice were immunized with either DC/UV-EB (n = 8) or Mφ/UV-EB (n = 8), UV-EBs alone (n = 8), or PBS alone (n = 7). Ten days after the immunization, mice were challenged with a sublethal dose of live chlamydial organisms, and mouse body weight was monitored on a daily basis for 10 days. (B) Titers of chlamydial infectious particles recovered from mouse lung tissues. Groups of mice as described for panel A and shown along the x axis were sacrificed 10 days after challenge infection. The infectious chlamydial organisms recovered from lung tissues were quantitated on HeLa cell monolayers as described in Materials and Methods.