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. Author manuscript; available in PMC: 2022 Nov 14.
Published in final edited form as: Aliment Pharmacol Ther. 2021 Dec 22;55(5):593–603. doi: 10.1111/apt.16733

TABLE 3.

Cox regression analysis of time to antibodies to infliximab (ATI) development

HR 95% CI P value
Age <10 years 1.86 0.99–3.49 0.05
Starting dose <7.5 mg/kg 2.09 0.98–4.45 0.05
Baseline Neutrophil CD64 activity ratio >6 2.55 1.14–5.70 0.02
Week 0–14 exposure (AUC) goal, 79 348 μg h/mL 0.48 0.27–0.84 0.009
HLA DQA*105 0.75 0.38–1.50 0.43

Abbreviations: AUC, area under concentration curve; CI, confidence interval; HR, hazard ratio.