Table 1.
CMV viremia present | CMV viremia absent | P-Valuea | |
---|---|---|---|
N per group | 121 | 219 | |
Women | 52 (43%) | 81 (37%) | 0.28 |
Age, years | 35 [29–40] | 35 [30–40] | 0.63 |
CD4+ T-cell count per μl | 14 [6–53] | 24 [8–61] | 0.07 |
CD4:CD8 ratio | 0.1 [0.0–0.1] | 0.1 [0.0–0.1] | 0.73 |
Receiving ART | 57 (47%) | 98 (45%) | 0.68 |
Months on ART | 2.5 [0.5–20] | 3.8 [1.1–32] | 0.22 |
CMV DNA, IU/ml | 452 [142–2450] | 0 [0–0] | |
Glasgow Coma Scale score <15 | 49 (41%) | 88 (40%) | 0.95 |
Hemoglobin, g/dl | 11.0 [9.5–12.6] | 11.6 [10.3–13.0] | 0.01 |
CSF white cells ≤5 cells/μl | 85 (73%) | 126 (60%) | 0.03 |
CSF opening pressure, mmH2 0 | 260 [180–370] | 270 [170–410] | 0.52 |
Randomized to Intervention | 76 (63%) | 151 (69%) | 0.07 |
Meningitis | 0.59 | ||
Cryptococcal meningitis (N = 308) | 111 (36%) | 197 (64%) | |
TB meningitis (N = 32) | 10 (31%) | 22 (69%) |
Data are N (%) or median [interquartile range].
P-values are from chi-square or Kruskal-Wallis testing.ART, antiretroviral therapy; mmH2 0, millimeters of water.