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. 2022 Nov 8;15:6125–6136. doi: 10.2147/JIR.S384977

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© 2022 Cheang et al.

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Variable importance (VIMP) and minimal depth (MD) from random survival forest analysis for cardiovascular mortality. (A) VIMP plot. Positive values indicate that including that variable in the model decreased the model’s error, whereas negative values indicate an increase in error. (B) For minimal depth, low values indicate that variable has stronger predictive value. (C) Comparison of the VIMP ranking and MD. Dashed vertical lines show the selected thresholds for variable selection. The farther the points are from the diagonal line, the more the discrepancy between measures; points above have higher VIMP ranking, indicating the variables are more sensitive to misspecification; those below have higher MD ranking, indicating they are better at dividing large portions of the population.

Abbreviations: IPS, inflammatory prognostic scoring; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; LYM, lymphocyte; CRP, C-reactive protein; MLR, monocyte-to-lymphocyte ratio; WBC, white blood cell; SIRI, systemic inflammatory response index; NLR, neutrophil-to-lymphocyte ratio; dNLR, derived neutrophil-to-lymphocyte; NEU, neutrophils; RDW, red cell distribution width; Mno, monocyte.