Table 4.
Factors Associated with Mortality in Adult Patient with HLH (Univariate and Multivariate Analysis)
| Variable | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | Adjusted OR | 95% CI | p-value | |
| Malignancy | 3.50 | 1.11–11.09 | 0.033 | |||
| Age | 1.05 | 1.01–1.09 | 0.005 | 1.053 | 1.016–1.092 | 0.005 |
| Sex | 0.31 | 0.097–0.98 | 0.046 | |||
| Mean ferritin | 1.000 | 1.00–1.00 | 0.230 | |||
| DIC | 6.00 | 1.59–22.61 | 0.008 | |||
| Platelets | 1.00 | 1.00–1.00 | 0.685 | |||
| Fibrinogen | 0.99 | 0.99–1.00 | 0.309 | |||
| Albumin <20 g/L | 0.38 | 0.06–2.31 | 0.297 | |||
| Natremia | 1.06 | 0.96–1.15 | 0.240 | |||
| Chemotherapy | 0.69 | 0.19–2.51 | 0.578 | |||
Abbreviations: OR, odds ratio; DIC, disseminated intravascular coagulation; CI, confidence interval.