Figure 5.

Replication with stricter motion exclusions. In this pipeline, we censored volumes with FD > 0.25 mm and excluded participants with average FD > 0.5 mm. a, Whole-brain measures of functional network segregation (system segregation, modularity, and the clustering coefficient) are significantly positively associated with age. The participation coefficient is a measure of functional network integration and is significantly negatively associated with age. b, Age effects on between-system connectivity. c, Number of edges from each parcel showing a significant positive age association; significance was defined as $p_{unc}<0.001$. d, Number of edges from each parcel showing a significant negative age association; significance was defined as $p_{unc}<0.001$. e, System-level associations with reasoning, controlling for age. Reasoning is associated with connectivity between the visual and dorsal attention systems and with connectivity between the default mode and dorsal attention systems. f, The number of edges from each parcel showing a significant positive reasoning association; significance was defined as $p_{unc}<0.001$. g, The number of edges from each parcel showing a significant negative reasoning association; significance was defined as $p_{unc}<0.001$. p_unc: uncorrected p value. Plots show 95% confidence intervals and partial residuals, controlling for in-scanner motion, sex, total number of volumes, and average network weight.