Table 1. Demographics and population characteristics of the entire cohort.
| Demographic factor | Entire cohort | Control | Intervention | p -Value a | |
|---|---|---|---|---|---|
| n (%) | 542 | 409 (75.5%) | 133 (24.5%) | ||
| Readmission, all cause | 65 (12.0%) | 57 (13.9%) | 8 (6.0%) | 0.015 | |
| Readmission, hyponatremia | 20 (3.7%) | 17 (4.2%) | 3 (2.3%) | 0.31 | |
| Admission age, y (mean ± SD) | 54.0 ± 16.4 | 53.9 ± 16.5 | 54.6 ± 16.2 | 0.65 | |
| Female sex | 294 (54.2%) | 219 (53.5%) | 75 (56.4%) | 0.57 | |
| Race | White | 348 (64.2%) | 262 (64.1%) | 86 (64.7%) | 0.99 |
| African American | 108 (19.9%) | 82 (20.0%) | 26 (19.5%) | ||
| Other | 86 (15.9%) | 65 (15.9%) | 21 (15.8%) | ||
| Hispanic | 224 (41.2%) | 163 (39.8) | 61 (45.9%) | 0.221 | |
| BMI (mean ± SD) | 30.0 ± 6.7 | 29.8 ± 6.7 | 30.4 ± 6.6 | 0.39 | |
| Functioning adenoma | 158 (31.0%) | 119 (39.2%) | 39 (33.6%) | 0.484 | |
| Tumor volume, cm 3 (mean ± SD) | 12.8 ± 17.1 | 12.8 ± 16.9 | 12.7 ± 17.9 | 0.94 | |
| Intraoperative CSF leak | Any leak | 296 (54.6%) | 218 (53.3%) | 78 (58.6%) | 0.28 |
| Low-flow leak | 199 (67.2%) | 153 (70.2% | 46 (59.0%) | 0.10 | |
| High-flow leak | 97 (32.8%) | 65 (29.8%) | 32 (41.0%) | ||
| Nasal septal flap | 69 (12.9%) | 50 (12.2%) | 19 (15.2%) | 0.39 | |
| Length of stay, d (mean ± SD) | 2.7 ± 1.9 | 2.8 ± 2.1 | 2.5 ± 1.4 | 0.17 | |
| Endocrine, inpatient | 467 (86.5%) | 340 (83.3%) | 127 (96.2%) | <0.001 | |
| Endocrine, outpatient | 380 (70.2%) | 278 (68.0%) | 102 (77.3%) | 0.042 | |
| Type of outpatient endocrine | Institution | 229 (59.8%) | 146 (52.1%) | 83 (80.6%) | <0.001 |
| Private | 154 (40.2%) | 134 (47.9%) | 20 (19.4%) | ||
| Postoperative diabetes insipidus | 236 (43.9%) | 183 (45.1%) | 53 (40.2%) | 0.32 | |
Abbreviations: BMI, body mass index; CSF, cerebrospinal fluid; SD, standard deviation.
Note: Values presented as number (%) unless otherwise indicated. Bold indicates statistically significant p -Values.
a
Reflects two-tailed t -test for continuous variables or a Pearson's chi-square/Fisher's exact test to compare categorical data between the groups.