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. 2022 Oct 7;83(6):626–634. doi: 10.1055/a-1920-0758

Table 2. Demographics and population characteristics of the intervention cohort stratified by readmission.

Demographic factor Intervention cohort Not readmitted Readmitted p -Value a
n (%) 133 (100%) 125 (94.0%) 8 (6.0%)
Readmission, hyponatremia 3 (2.3%) 3 (37.5%)
Admission age, y (mean ± SD) 54.6 ± 16.2 55.2 ± 14.7 44.7 ± 31.7 0.075
Sex (female) 75 (56.4%) 70 (56.0%) 5 (62.5%) 0.72
Race White 86 (64.7%) 80 (64.0%) 6 (75.0%) 0.81
Hispanic 61 (45.9) 58 (46.4%) 3 (37.5%) 0.624
BMI (mean ± SD) 30.4 ± 6.6 30.5 ± 6.6 28.7 ± 6.1 0.44
Length of stay, d (mean ± SD) 2.5 ± 1.4 2.5 ± 1.4 2.6 ± 0.7 0.79
Functioning adenoma 39 (33.0%) 36 (33.0%) 3 (42.9%) 0.594
Histology Lactotroph 17 (12.9%) 16 (12.9%) 1 (12.5%) 0.86
Somatotroph 6 (4.5%) 6 (4.8%) 0 (0.0%)
Corticotroph 19 (14.4%) 18 (14.5%) 1 (12.5%)
Gonadotroph 59 (44.7%) 56 (45.2%) 3 (37.5%)
Multiple 31 (23.5%) 28 (22.6%) 3 (37.5%)
Intraoperative CSF leak Any leak 78 (58.6%) 73 (58.4%) 5 (62.5%) 0.82
Low-flow leak 46 (34.6%) 45 (61.6%) 1 (20%) 0.067
High-flow leak 32 (24.1%) 28 (38.4%) 4 (75%)
Nasal septal flap 19 (15.2%) 17 (14.5%) 2 (25.0%) 0.42
Tumor volume, mm 3 (mean ± SD) 12,656.2 ± 17,869.0 12,569.2 ± 17,821.2 14,048.7 ± 20,041.6 0.83
Endocrine, inpatient 127 (96.2%) 120 (96.8%) 7 (87.5%) 0.18
Endocrine, outpatient 102 (77.3%) 96 (77.4%) 6 (75.0%) 0.87
Type of outpatient endocrine University of Miami 83 (80.6%) 78 (80%) 5 (83%) 0.86
Private 20 (19.4%) 19 (20%) 1 (17%)
Serum sodium checked 81 (62.3%) 75 (60.0% 6 (75%) 0.217
Serum sodium, mmol/L (mean ± SD) 139.0 ± 4.1 139.4 ± 3.6 135.0 ± 6.7 0.004
Hyponatremia Any 11 (14%) 10 (13.3%) 1 (16.7%) 0.040
Mild 9 (11.1%) 9 (12%) 0 (0%)
Moderate 2 (2.5%) 1 (1.3%) 1 (16.7%) <0.001
Postoperative diabetes insipidus 53 (40.2%) 47 (37.9%) 6 (75.0%) 0.038

Abbreviations: BMI, body mass index; CSF, cerebrospinal fluid; SD, standard deviation.

Note: Values presented as number (%) unless otherwise indicated. Bold indicates statistically significant p -Values.

a

Reflects two-tailed t -test for continuous variables or a Pearson's chi-square/Fisher's exact test to compare categorical data between the groups.