Table 3.
Select common (≥ 4%) adverse events by cohorta
| Preferred term, n (%) | Rollover cohort (n = 82) | Switch cohort (n = 37) |
|---|---|---|
| Fall | 31 (38) | 16 (43) |
| Depression | 26 (32) | 8 (22) |
| Anxiety | 22 (27) | 13 (35) |
| Insomnia | 19 (23) | 6 (16) |
| Somnolence | 16 (20) | 11 (30) |
| Urinary tract infection | 12 (15) | 4 (11) |
| Weight decreased | 11 (13) | 9 (24) |
| Diarrhea | 11 (13) | 7 (19) |
| Irritability | 11 (13) | 4 (11) |
| Nasopharyngitis | 8 (10) | 6 (16) |
| Nausea | 8 (10) | 3 (8) |
| Chorea | 7 (9) | 7 (19) |
| Dysphagia | 7 (9) | 6 (16) |
| Constipation | 7 (9) | 5 (14) |
| Laceration | 7 (9) | 5 (14) |
| Akathisia | 5 (6) | 4 (11) |
| Dry mouth | 4 (5) | 4 (11) |
| Pneumonia | 1 (1) | 7 (19) |
| Decreased appetite | 1 (1) | 4 (11) |
aA complete listing of common adverse events (≥ 4%) is available in the ESM