Table 4.
Change in UHDRS TMC score | Change in UHDRS TMS | |
---|---|---|
Change from baseline to week 8 | ||
Rollover cohort | − 4.4 (3.1) | − 7.1 (7.3) |
Switch cohort | − 2.1 (3.3) | − 2.4 (8.7) |
Change from week 8 to week 145a | ||
All subjects | − 0.5 (5.2) | 8.2 (11.9) |
Values shown are mean (SD)
SD standard deviation, TMC total maximal chorea, TMS total motor score, UHDRS Unified Huntington’s Disease Rating Scale
aThe Rollover and Switch cohorts were analyzed separately from baseline through week 8. The two cohorts were combined for the analysis of changes from week 8 to week 145 (or the last visit on the study drug, if that occurred earlier)