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. 2022 Jun 25;227(9):2971–2989. doi: 10.1007/s00429-022-02519-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Associations found between F1/F2 and the connectivity of SN/DMN hubs. We observed a negative association between F1 and the seed-based connectivity of SN hubs and on the opposite, a positive association between F2 and the seed-based connectivity of two DMN hubs. N = 34 (bvFTD: N = 18/controls: N = 16). Effects are corrected for age and sex, and for family-wise error at the level of individual clusters at P < 0.05. SBC, seed-based connectivity; F1, global reduction of goal-directed behaviors; F2, specific deficit of self-initiation