Table 1.
Lineage-specific differentially expressed genes identified by CLIMB are enriched in gene ontology terms related to terminal cell function
| Lineage | Gene ontology term | FDR |
|---|---|---|
| Erythroid | Heme biosynthetic process | 4.71 × 10−3 |
| Heme metabolic process | 4.08 × 10−4 | |
| Erythrocyte differentiation | 3.19 × 10−3 | |
| Response to oxygen-containing compound | 1.57 × 10−4 | |
| Megakaryocytic | Platelet activation | 4.30 × 10−3 |
| Regulation of blood coagulation | 1.25 × 10−3 | |
| Response to wounding | 2.58 × 10−5 | |
| Regulation of homotypic cell–cell adhesion | 4.16 × 10−2 | |
| Myeloid | Pos. regulation of monocyte chemotaxis | 6.91 × 10−3 |
| Leukocyte differentiation | 1.15 × 10−9 | |
| Neutrophil migration | 6.11 × 10−6 | |
| Regulation of macrophage activation | 1.46 × 10−3 |