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. 2022 Nov 12;12:19387. doi: 10.1038/s41598-022-23957-5

Table 2.

Salivary and periodontal parameters according to OSA severity.

No OSA
N = 17
Mild to moderate OSA
N = 109
Severe OSA N = 79 p
Salivary parameters
Salivary flow (ml/min) 0.244 (0.15–0.39) 0.23 (0.15–0.36) 0.22 (0.14–0.41) 0.918
Salivary pH 6.58 (6.47–6.74) 6.59 (6.36–6.84) 6.64 (6.33–7) 0.286
Salivary calcium (mmol/L) 0.61 (0.47–0.8) 0.51 (0.38–0.69) 0.52 (0.39–0.69) 0.590
Salivary phosphate (mmol/L) 6.39 (4.31–8.24) 6.19 (5.04–7.49) 6.43 (4.64–8.85) 0.801
Salivary magnesium (mmol/L) 0.2 (0.15–0.31) 0.19 (0.14–0.27) 0.19 (0.14–0.27) 0.874
Ca/Mg 2.67 (2.15–3.03) 2.59 (1.95–3.8) 2.62 (1.88–4.12) 0.991
Ca/PO4 0.09 (0.08–0.11) 0.09 (0.06–0.12) 0.08 (0.06–0.12) 0.842
Mg/PO4 0.03 (0.03–0.04) 0.03 (0.02–0.04) 0.03 (0.02–0.04) 0.678
Salivary cortisol (ng/mL) 6.25 (5.156–8.13) 1 4.64 (3.032–5.75) 2 4.57 (3.11–6.06) 2 0.011
N = 11 N = 87 N = 59
Periodontal status
Number of teeth 28 (25.5–28) 1 23 (17–27) 2 22 (15.5–25.5) 2 0.019
Plaque (%) 38 (29.5–51) 1 59 (46–78) 1 73 (59.3–94) 1 0.001
BoP (%) 20 (6–45) 21 (10–32) 20 (12.3–36) 0.957
CAL (mm) 2.3 (2–2.7) 2.6 (2.2–3) 2.7 (2.1–3.4) 0.175
PISA score (mm2) 173.7 (67.1–546.4) 218.3 (89.5–368.8) 179.7 (86.65–344.94) 0.953
Stages of periodontitis
No periodontitis 3 (27.3) 7 (9.1) 7 (13) 0.095
Periodontitis stages 1 and 2 6 (54.5) 33 (42.9) 20 (37)
Periodontitis stages 3 and 4 2 (18.2) 37 (48.1) 27 (50)

Data are presented as the medians with interquartile ranges. The Kruskal‒Wallis test was calculated for group comparisons.

1Post hoc difference to both other groups following the Mann‒Whitney U test p < 0.05.

2Post hoc difference only to the no OSA group following the Mann‒Whitney U test p < 0.05.