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. 2022 Nov 12;12:19387. doi: 10.1038/s41598-022-23957-5

Table 3.

Salivary and periodontal parameters according to salivary flow rate.

Hyposalivation (flow rate less than 0.1 mL/min) N = 25 Reduced salivation (flow rate 0.1–0.3 mL/min) N = 97 Normal salvation (flow rate more than 0.3 mL/min) N = 66 p
Age (years) 61 (53–70) 60 (52–68) 58.5 (49–66.75) 0.487
Sex
Male 14 (56%) 69 (71.1%) 52 (78.8%) 0.095
Female 11 (44%) 28 (28.9%) 14 (21.2%)
BMI (kg/m2) 31.6 (27.1–36.8) 29.7 (26.2–32.9) 30.1 (27.82–32.92) 0.283
AHI (events/h) 26.8 (10.9–46.8) 20.1 (11–34.9) 19.5 (10.52–36.5) 0.672
Salivary parameters
Salivary pH 6.36 (6.06–6.78) 3 6.53 (6.3–6.76) 3 6.89 (6.62–7.16) 1,2  < 0.001
Salivary calcium (mmol/L) 0.67 (0.47–0.94) 3 0.56 (0.41–0.71) 3 0.42 (0.34–0.57) 1,2  < 0.001
Salivary phosphate (mmol/L) 8.38 (4.91–11.27) 3 6.93 (5.48–8.77) 3 5.35 (4.46–6.43) 1,2  < 0.001
Salivary magnesium (mmol/L) 0.42 (0.34–0.6) 2,3 0.2 (0.16–0.25) 1,3 0.15 (0.1–0.19) 1,2  < 0.001
Ca/Mg 1.8 (1.35–2.48) 2,3 2.65 (1.92–3.78) 1 3 (2.15–4.67) 1  < 0.001
Ca/PO4 0.09 (0.06–0.12) 0.09 (0.06–0.12) 0.09 (0.06–0.12) 0.842
Mg/PO4 0.05 (0.03–0.06) 2,3 0.03 (0.02–0.04) 1 0.03 (0.02–0.03) 1  < 0.001
Salivary cortisol (ng/mL) 5.44 (4.59–6.58) 3 5.02 (3.59–6.13) 3 3.88 (1.7–5.56) 1,2 0.003
N = 17 N = 75 N = 50
Periodontal status
Number of teeth 20 (16–24) 21 (16–27) 24 (18–27) 0.269
Plaque (%) 59 (52–100) 63 (49.5–80.5) 67 (53.5–80.5) 0.894
BoP (%) 27 (14–29) 22 (12.5–37) 17 (7.5–28.5) 0.234
CAL (mm) 2.5 (2.3–3) 2.7 (2.3–3) 2.6 (1.95–3.05) 0.573
PISA score (mm2) 240.2 (111.1–349.8) 238.29 (94.22–373.1) 147.6 (74.6–331.4) 0.245

Data are presented as the medians with interquartile ranges. The Kruskal‒Wallis test was used for group comparisons.

1Post hoc difference significant to < 0.1 per group following the Mann‒Whitney U test.

2Post hoc difference significant to 0.1–0.3 per group following Mann‒Whitney U test.

3Post hoc difference significant to > 0.3 per group following Mann‒Whitney U test.