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. 2022 Nov 12;9:696. doi: 10.1038/s41597-022-01815-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Metadata template for capturing information about a tissue sample. This screen capture shows the template used by investigators in the NIH-supported HuBMAP consortium to specify metadata about biological specimens used to perform assays of cell-specific biomarkers. In the figure, the user is entering a controlled term from a special HuBMAP ontology to provide the metadata entry for the specimen’s preparation medium. The attributes of tissues are the ones that the HuBMAP community has chosen to standardize for its descriptions of such samples. The ontology terms used to provide values for the metadata attributes similarly represent community-endorsed standards for declaring this kind of information.