OS	Osteosarcoma
MSTS	Musculoskeletal tumors
AJCC	American Joint Committee on Cancer
EFS	Event-free survival
NK	Natural killer cell
NKT	Natural killer T cell
COG	Children’s Oncology Group
PI3K	Phosphoinositide-3 kinase
PIK3CA	Phosphatidylinositol 3-kinase
mTOR	Mechanistic target of rapamycin
IGF	Insulin-like growth factor
IGF-1R	Insulin-like growth factor 1 receptor
VEGF	Vascular endothelial growth factor
VEGFA	Vascular endothelial growth factor A
KDR	Kinase insert domain receptor
PDGF	Platelet-derived growth factor
PDGFR	Platelet-derived growth factor receptor
DDR	DNA damage response
KIT	KIT proto-oncogene receptor tyrosine kinase
MYC	Avian myelocytomatosis viral oncogene homolog
CDK	Cyclin-dependent kinase
CCNE1	Cyclin E1
CCND2	Recombinant human cyclin-D2
PTEN	Phosphatase and tensin homolog deleted on chromosome ten
ADP	Adenosine diphosphate
PARP	Poly ADP-ribose polymerase
TP53	Tumor protein p53
RB1	Retinoblastoma1
PDX	Patient-derived xenograft
PDOX	Patient-derived orthotopic xenograft
ADR	Adriamycin
SCID	Server combined immune-deficiency
MEK	Mitogen-activated protein kinase kinase
MAPK	Mitogen-activated protein kinase
GPNMB	Glycoprotein non-metastatic melanoma protein B
CAR-T	Chimeric antigen receptor T
HER2	Human epidermal growth factor receptor-2
BsAb	Bispecific antibody