Table 1.
Changes in the physical activity of animals as a percentage of the initial value.
Start | End of Injection | 1st Month | 2nd Month | |
---|---|---|---|---|
Control | 100% | 87% | 79% | 94% |
DOX | 100% | 65% * | 55% * | 50% * |
NR+DOX | 100% | 61%* | 64% * | 58% * |
NR/NR+DOX | 100% | 80% | 71% | 69% |
DOX represents doxorubicin; NR represents nicotinamide riboside. *—p < 0.05, significant difference compared to the initial value (start of the experiment). Control represents control group (n = 15); DOX represents doxorubicin group (n = 15); NR+DOX represents nicotinamide riboside + doxorubicin group—combined mode (n = 15); and NR/NR+DOX represents nicotinamide riboside/nicotinamide riboside + doxorubicin group—preventive mode (n = 15).