Table 2.
The characteristic degradation parameters, half time (t1/2), degradation rate (k), with the estimated standard deviations (SD), calculated by conventional quantitative or LEDA processing of the data from the series of spiked human plasma samples.
| Pure Isomer t1/2 ± 2SD (min) |
Pure Isomer k ± 2SD (ln(μM)/min) |
Mix t1/2 ± 2SD (min) |
Mix k ± 2SD (ln(μM)/min) |
|
|---|---|---|---|---|
| FRA76 | 43 ± 16 | −0.017 ± 0.001 | 32 ± 18 | −0.019 ± 0.003 |
| GDE5 | >120 | <0.006 | >120 | <0.006 |
| ELF94 | 49 ± 18 | −0.014 ± 0.001 | 34 ± 14 | −0.023 ± 0.005 |
| ELF96 | >120 | <0.006 | >120 | <0.006 |