TABLE 2.
Anti-Spe antibodies in patients with severe and nonsevere invasive group A streptococcal infections
| ELISA antigen | Level of anti-Spe antibodies in plasma (mean ELISA titer ± SEM) for:
|
|||
|---|---|---|---|---|
| Healthy individuals (n = 20) | All invasive cases (n = 33) | Severe invasive cases (n = 21) | Nonsevere invasive cases (n = 12) | |
| SpeA | 114 ± 14 | 72 ± 6 (P < 0.003a) | 67 ± 8 (P < 0.002a) | 80 ± 10 (P < 0.025ab; P = 0.15ab) |
| SpeB | 60 ± 6 | 28 ± 6 (P < 0.0002a) | 23 ± 7 (P < 0.0001a) | 37 ± 8 (P < 0.004ab; P = 0.111ab) |
| SpeF | 153 ± 16 | 90 ± 10 (P < 0.001a) | 83 ± 13 (P < 0.0008a) | 103 ± 15 (P < 0.016ab; P = 0.15ab) |
a
Versus results for age-matched healthy individuals.
b
Versus results for severe invasive cases.