Table 1.
Patient characteristics. Tabular overview on clinical data of the ten included PCFBCL patients and two further arbitrary cases (cases #2 and #3)—being finally reclassified as PCMZL—with immunohistochemical and molecular findings of respective analyzed tissue specimen.
| Pat ID | Sex | Age at Primary Diagnosis [Years] | Tumor Stage at Primary Diagnosis | Tumor Stage at Date Last Seen | Cutaneous Relapses | Number of Cutaneous Relapses | Systemic Dissemination | Treatment | Overall Survival Since Primary Diagnosis [Months] | Final Status | Clonality | bcl-2 Expression Immunohistochemistry | bcl2 FISH Analysis |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | male | 39 | T2 N0 M0 | T2 N0 M0 | yes | 1 | no | rituximab | 117 | alive | polyclonal | negative | negative |
| 2 | male | 60 | T2c N0 M0 | T2c N0 M0 | no | no | rituximab | 75 | dead | polyclonal | positive | negative | |
| 3 | female | 70 | T2 N0 M0 | T2 N0 M0 | no | no | rituximab | 131 | alive | oligoclonal/polyclonal | positive | negative | |
| 4 | male | 54 | T1 N0 M0 | T2 N0 M0 | yes | 3 | no | excision, radiation | 200 | alive | oligoclonal/polyclonal | negative | negative |
| 5 | female | 70 | T2 N0 M0 | T2b N0 M0 | yes | >5 | no | excision, radiation, topical steroids, rituximab | 117 | alive | monoclonal | positive | negative |
| 6 | female | 66 | T1 N0 M0 | T1 N0 M0 | no | no | watch-and-wait | 66 | alive | not done | negative | negative | |
| 7 | female | 89 | T1b N0 M0 | T1b N0 M0 | no | no | radiation | 47 | alive | not done | negative | negative | |
| 8 | male | 45 | T1a N0 M0 | T1a N0 M0 | no | no | excision | 23 | alive | polyclonal | positive | negative | |
| 9 | male | 50 | T1a N0 M0 | T1a N0 M0 | no | no | radiation | 21 | alive | not done | positive | positive | |
| 10 | male | 50 | T1 Nx Mx | T1 Nx Mx | no | no | watch-and-wait | 57 | alive | monoclonal | negative | negative | |
| 11 | female | 53 | T2 N0 M0 | T2 N0 M0 | yes | 2 | no | radiation, topical steroids | 35 | alive | not done | negative | negative |
| 12 | male | 43 | T2 N0 M0 | T2 N0 M0 | no | no | rituximab | 107 | alive | not done | negative | negative |