Figure 1.
The effects of the pharmacodynamic activity of puerarin and metformin and the pharmacodynamic interaction between puerarin and metformin on serum biochemical parameters. (A) Hyperglyceamia, (B) cholesterol, (C) triglycerides, (D) HDL, (E) LDL, (F) urea, (G) creatinine, (H) ALT, (I) AST, (J) ALP. The groups are represented as follows: NC, normal control; DC, diabetic control; P1, puerarin (80 mg/kg); P2, puerarin (120 mg/kg); P3, puerarin (160 mg/kg); M, metformin (100 mg/kg); P1M, puerarin (80 mg/kg) + metformin (100 mg/kg); P2M, puerarin (120 mg/kg) + metformin (100 mg/kg); P3M, puerarin (160 mg/kg + metformin (100 mg/kg).The annotations on the pairwise comparisons are as follows: ns, not significant (p > 0.05); *, p ≤ 0.05; **, p ≤ 0.01; ***, p ≤ 0.001; ****, p ≤ 0.0001.