Table 3.

Candidate protein signatures derived from DSP.

SEQ	Protein	p_Value	AUROC	Sensitivity	Specificity	Accuracy	PPV	NPV
1	CD68_HLA.DR_OX40L_Phospho.c.RAF_STING_Tim.3	1.16 × 10−6	0.873	81.82	93.55	87.50	93.10	82.86
2	ARG1_B7.H3_CD127_CD68_HLA.DR_OX40L_pan.RAS_STING_Tim.3	5.19 × 10−7	0.894	87.88	83.87	85.94	85.29	86.67
3	B7.H3_CD68_HLA.DR_OX40L_Phospho.c.RAF_STING_VISTA	5.19 × 10−7	0.874	87.88	83.87	85.94	85.29	86.67
4	Beta.2.microglobulin_CD127_CD68_HLA.DR_OX40L_Tim.3	5.06 × 10−7	0.878	84.85	87.10	85.94	87.50	84.38
5	CD68_HLA.DR_OX40L_pan.RAS_STING	5.06 × 10−7	0.870	84.85	87.10	85.94	87.50	84.38

Abbreviation: AUROC, area under receiver operating characteristic curve; NPV, negative predictive value; PPV, positive predictive value; SEQ, sequence.