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. 2022 Oct 31;14(21):5381. doi: 10.3390/cancers14215381

Figure 1.

Figure 1

The expression of IGF2BP2 in GC tissues is remarkably upregulated, which predicts poor survival in GC patients. (A,B) The data from the TCGA database show the expression levels of IGF2BP2 in unpaired or paired GC and normal gastric tissues. (C) Expression levels of IGF2BP2 in paired GC and normal gastric tissues detected RT-PCR. (D) Representative results of the IGF2BP2 protein upregulation in GC specimens determined by Western blotting. (E) The correlation of high or low IGF2BP2 expression with the overall survival of GC patients according to the Kaplan–Meier plotter database. (F) Representative results of immunohistochemical staining of IGF2BP2 in GC specimens (200×). (G,H) The expression of IGF2BP2 upregulation was obviously related to poor overall survival and relapse-free survival in GC patients through Kaplan–Meier survival analysis. * p < 0.05, *** p < 0.001. Molecular weights for proteins are shown in the uncropped Western blot images (Figure S1).