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. 2022 Oct 31;14(21):5381. doi: 10.3390/cancers14215381

Table 1.

Correlations between IGF2BP2 expression and clinicopathologic parameters of 173 GC patients.

Characteristics No. IGF2BP2 Expression χ2 p ρ p
Low (N = 81) High (N = 92)
Age 52.44 ± 11.98 58.38 ± 12.57
<60 y 103 60 43 13.36 0.000 *** 0.278 0.000 ***
≥60 y 70 21 49
Gender
Male 116 54 62 0.01 0.919 −0.008 0.920
Female 57 27 30
Tumor location
Proximal 41 17 24 1.843 0.606 0.003 0.967
Middle 41 22 19
Distal 75 36 39
More than 2 16 6 10
Tumor size
<5 cm 71 40 31 4.381 0.036 0.159 0.037 *
≥5 cm 102 41 61
Histologic type
Adenocarcinoma 151 71 80 1.410 0.842 0.014 0.859
Squamous 1 1 0
Signet ring 11 5 6
Mucinous 7 3 4
Undifferentiated 3 1 2
Borrmann classification
12 6 6 6.169 0.104 0.170 0.026 *
40 24 16
102 46 56
19 5 14
Differentiation
High 2 1 1 0.621 0.733 −0.056 0.464
Moderate 41 17 24
Poor 130 63 67
Depth of invasion
T1 19 13 6 5.283 0.152 0.160 0.035 *
T2 21 11 10
T3 98 44 54
T4 35 13 22
Lymph-node metastasis
N0 48 31 17 8.533 0.036 * 0.191 0.012 *
N1 73 30 43
N2 32 12 20
N3 20 8 12
Distant metastases
M0 131 66 65 2.748 0.097 0.126 0.098
M1 42 15 27
AJCC pTNM
33 22 11 7.451 0.059 0.184 0.015 *
62 28 34
36 16 20
42 15 27

ρ , Spearman’s rank correlation coefficient. * p < 0.05, *** p < 0.001.