Table 1.
The size and ζ-potential of CD, CDpol and their complexes with liposomes, pH 7.4 (0.02 M Na-phosphate buffer solution), 22 °C.
| Size, nm | ζ-Potential, mV | Mr, kDa | Number of CDs per 1 Particle | ζ-Potential of Liposomes + CD, mV |
|
|---|---|---|---|---|---|
| HPCD | 0.15 1 | 0.5 ± 0.1 | 1.5 | − | −18.2 ± 4.4 |
| HPCDpol | 110 ± 15 | 9.2 ± 1.2 | 100 ± 15 | 67 ± 11 | −14.3 ± 3.3 |
| MCD | 0.15 1 | 0.7 ± 0.2 | 1.2 | − | −19.6 ± 3.4 |
| MCDpol | 165 ± 15 | 22.9 ± 1.2 | 130 ± 15 | 100 ± 15 | −12.2 ± 2.3 |
| SBECD | 0.15 1 | −7.7 ± 0.5 | 2.1 | − | −24.8 ± 3.9 |
| SBECDpol | 110 ± 15 | −13.4 ± 0.9 | 115 ± 13 | 65 ± 8 | −14.2 ± 3.3 |
| AMCD | 0.15 1 | 6.2 ± 1.2 | 1.6 | − | −18.5 ± 3.6 |
| AMCDpol | 122 ± 17 | 10.2 ± 2.2 | 122 ± 15 | 70 ± 11 | −13.5 ± 2.2 |
| Liposomes DPPC:Cl = 80:20 (weight %) | 105 ± 7 | −20.9 ± 3.2 | − | − | − |
1 The size of CD derivatives is assumed to be close to the size of the parent CD [26].