MetaCore protein network built by processing significant protein differences occurring among Twi, Het, and wild-type mice. Experimental proteins, circled in blue, were cross-linked by using the shortest-path-network (SPN) building tool. This generates hypothetical networks by cross-linking experimental factors and expanding protein interactions to other proteins, not present in the processed experimental list but supported by the MetaCore database, that are needed to functionally correlate user up-loaded proteins, which do not directly interact. Except for tropomodulin-2, all the processed proteins entered into the SPN.