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. 2022 Nov 1;23(21):13348. doi: 10.3390/ijms232113348

Table 5.

Summary of animal research focusing on oxidative stress.

No. Strain Sex Age Physical Activity Stress Model Main Outcome Reference
1 C57/B16J female 8 weeks voluntary wheel running restraint stress Enhanced expression of proapoptotic Bax protein in the mouse cortex and microglia/macrophage expression of Cox-2 in the hippocampus [116]
2 Wistar male 45–48 days treadmill sleep deprivation increased protein expression of GLO1 and GSR1 in the amygdala, cortex, and hippocampus; ameliorated anxiety-like behaviour [115]
3 Wistar male 3 weeks treadmill chronic stress restraint and forced swim stress improved aversive memory and oxidative status changes in the amygdala and hippocampus, Na+, K+-ATPase activity in the hippocampus [117]

GLO1—glyoxalase 1; GSR1—glutathione reductase 1; LC—locus coeruleus.