Table 1.

Number of residues in the intersection between different numbers of top-ranking residuals (first column) associated with various centrality measures (first row) such as Residue Centrality Analysis (RCA), Betweenness Centrality Analysis (BCA), Closeness Centrality Analysis (CCA), and those belonging to the four pockets. In the parentheses, the p-value associated with the relevance of the intersection value.

	RCA	BCA	CCA	Z-RCA
10	5 (2.1·10−4)	6 (2.5·10−4)	5 (2.1·10−4)	6 (2.5·10−4)
20	10 (8.3·10−5)	9 (5.1·10−4)	10 (8.3·10−5)	9 (5.1·10−4)
50	19 (3.7·10−5)	20 (8.9·10−6)	19 (3.7·10−5)	18 (1.4·10−4)