FIG. 1.

Effect of supernatants from CD40L-activated SC cultures on T. cruzi infection of MPM. Supernatants harvested from SC (open bars), from SC incubated with 3T3 control fibroblasts (hatched bars), or from CD40L-activated SC (black bars) were added to MPM at the time of T. cruzi infection, in the presence or absence of NAME, and the parasitic index (A) and nitrite levels (B) were measured. Data are means ± standard deviations from three independent experiments performed in duplicate. ∗∗∗, P < 0.001 compared to 3T3 control fibroblasts (Student’s t test).