TABLE 2.

Production of IL-12 p40 and IL-12 p70 by SC incubated with 3T3-CD40L transfectants^a

Treatment of SC	IL-12 p40 (pg/ml)	IL-12 p70 (pg/ml)
None	3,052 ± 1,079	<15
3T3	5,852 ± 3,201	<15
3T3-CD40L	34,266 ± 10,523*	63.8 ± 35.3*

^aSC were incubated with either 3T3 control fibroblasts or 3T3-CD40L transfectants for 48 h. IL-12 p40 and IL-12 p70 levels were measured in culture supernatants. Data are means ± standard deviations from three (IL-12 p40) and five (IL-12 p70) independent experiments performed in duplicate. ∗, P < 0.05 compared to 3T3 control fibroblasts (Student’s t test).