Table 2.
The absolute risk and attributable proportion of different HPV types by cytology.
| HPV Type | NILM | LSIL | Relative Risk | HSIL+ | Relative Risk | |||
|---|---|---|---|---|---|---|---|---|
| Absolute Risk (%) | Attribute Fraction (%) | Absolute Risk (%) | Attribute Fraction (%) | Absolute Risk (%) | Attribute Fraction (%) | |||
| HPV6 | 0.7 (0.5–0.1) | 0.5 (0.4–0.8) | 2.8 (1.3–6.1) | 0 | 0 | 0.7 (0.2–3.8) | 0 | 0 |
| HPV11 | 0.2 (0.1–0.4) | 0.1 (0.1–0.3) | 1.4 (0.5–4.0) | 0 | 0 | 0.7 (0.2–3.8) | 0 | 0 |
| HPV16 | 2.6 (2.2–3.0) | 2.1 (1.8–2.5) | 16.6 (12.3–22.0) | 12.7 (8.9–17.7) | 6.0 | 46.3 (38.4–54.3) | 44.3 (36.5–52.4) | 21.1 |
| HPV18 | 1.0 (0.7–1.3) | 0.7 (0.5–1.0) | 5.4 (3.10–9.17) | 3.2 (1.5–6.4) | 4.6 | 8.8 (5.2–14.5) | 5.6 (2.9–10.6) | 8.0 |
| HPV31 | 1.1 (0.8–1.4) | 0.1 (0.1–0.3) | 10.0 (4.5–8.06) | 3.5 (1.8–6.9) | 35 | 2.0 (0.7–5.8) | 2.0 (0.7–5.8) | 20 |
| HPV33 | 0.6 (0.4–0.8) | 0.4 (0.3–0.7) | 1.8 (0.70–4.52) | 0.6 (0.12–2.69) | 1.5 | 4.1 (1.9–8.6) | 2.5 (0.9–6.5) | 6.3 |
| HPV35 | 0.5 (0.4–0.8) | 0.3 (0.2–0.5) | 3.6 (1.83–6.92) | 1.2 (0.37–3.62) | 4.0 | 0 | 0 | 0 |
| HPV39 | 1.1 (0.8–1.4) | 0.8 (0.6–1.1) | 6.3 (3.78–10.26) | 3.8 (1.9–7.1) | 4.8 | 2.1 (0.7–6.2) | 0 | 0 |
| HPV45 | 0.4 (0.3–0.6) | 0.3 (0.2–0.5) | 0.9 (0.25–3.21) | 0.5 (0.1–2.5) | 1.7 | 0 | 0 | 0 |
| HPV51 | 1.7 (1.4–2.1) | 1.3 (1.0–1.6) | 7.2 (4.46–11.34) | 5.8 (3.4–9.7) | 4.5 | 6.1 (3.3–11.2) | 3.0 (1.2–7.1) | 2.3 |
| HPV52 | 3.2 (2.8–3.8) | 2.8 (2.4–3.3) | 13.9 (9.97–19.06) | 10.1 (6.8–14.8) | 3.6 | 14.3 (9.5–20.6) | 8.6 (5.1–14.3) | 3.1 |
| HPV56 | 1.0 (0.8–1.3) | 0.7 (0.5–1.0) | 11.7 (8.08–16.54) | 8.0 (5.1–12.3) | 11.4 | 0.7 (0.1–3.9) | 0 | 0 |
| HPV58 | 1.2 (1.0–1.6) | 1.0 (0.7–1.3) | 9.4 (6.24–13.97) | 8.5 (5.5–12.9) | 8.5 | 16.3 (11.2–23.1) | 14.8 (10.0–21.5) | 14.8 |
| HPV59 | 0.6 (0.4–0.9) | 0.5 (0.3–0.7) | 3.6 (1.83–6.92) | 2.5 (1.2–5.6) | 5.0 | 0.7 (0.1–3.9) | 0 | 0 |
| HPV66 | 1.4 (1.1–1.8) | 1.0 (0.7–1.3) | 8.1 (5.17–12.40) | 6.9 (4.3–11.0) | 6.9 | 1.4 (0.4–4.8) | 0 | 0 |
| HPV68 | 1.1 (0.8–1.4) | 0.8 (0.6–1.1) | 4.0 (2.14–7.49) | 1.3 (0.4–3.8) | 1.6 | 2.0 (0.7–5.8) | 1.4 (0.4–4.9) | 1.8 |
Note: The figures in the brackets represent 95% confidence interval; negative for intraepithelial lesion or malignancy (NILM); low-grade squamous intraepithelial lesions (LSIL); high-grade squamous intraepithelial lesions or above (HSIL+).