Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Possible beneficial targets in ACE2-mediated SARS-CoV-2 infection. SARS-CoV-2 binds the cell receptor ACE-2 to facilitate entry after the spike protein is primed by membrane protease. The virus then replicates abundantly, producing replicates that efflux from host cells, resulting in damage and spreading. Potential therapeutic approaches include the use of a soluble form of ACE2 that competitively binds viruses.
