Table 4.

The cumulative risks of disease relapse in HPV-related oropharyngeal cancer by alcohol and smoking age.

Smoking Age	Follow-Up	p16 (+)
		Absolute Risk (95% CI)	Absolute Risk (95% CI)
		Alcohol (−)	Alcohol (+)
<20 pack-years	3 years	0.12 (0.11, 0.14)	0.33 (0.24, 0.39)
	5 years	0.14 (0.12, 0.15)	0.35 (0.26, 0.42)
20–29 pack-years	3 years	0.19 (0.18, 0.20)	0.45 (0.35, 0.51)
	5 years	0.21 (0.20, 0.21)	0.47 (0.37, 0.54)
≥30 pack-years	3 years	0.22 (0.21, 0.24)	0.50 (0.38, 0.57)
	5 years	0.24 (0.22, 0.25)	0.52 (0.41, 0.59)

Abbreviations: HPV, human papilloma virus; CI, confidence interval.