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. 2022 Oct 27;11(21):3392. doi: 10.3390/cells11213392

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Ovarian cancer ascites increase human EOC cell proliferation, migration, and invasion (A2780, HO8910, SKOV3, and HEY) in vitro. (A). The effect of ascites on human EOC cell line proliferation was measured by EdU assay. (B). The effect of ascites on human EOC cell migration was measured by Transwell assay. (C). The effect of ascites on human EOC cell invasion was measured by Transwell assay. (D). Quantification of proliferation rates showed that the proliferative capacity of human EOC cell lines was significantly improved after ascites treatment. (E). Quantification of the migrated cells showed that human EOC cell migratory capacity was significantly improved after ascites treatment. (F). Quantification of the invasion rates of human EOC cell lines showed that the invasive capacity of human EOC cell lines was significantly improved after ascites treatment. * p < 0.05, n = 3.