Table 1.

Criteria for risk stratification of recurrence and death of patients diagnosed with breast cancer (based on Goldhirsch et al. [4]).

Low risk	Negative lymph nodes and all the following criteria:
	pT under 2 cm;
	Histological grade 1;
	ER or PR positive;
	HER-2 negative;
	Molecular subtype luminal A; and
	Age equal to or above 35 years old.
Intermediate risk	Negative lymph nodes and at least one of the following criteria:
	pT higher than 2 cm; or
	Histological grade 2–3; or
	ER or PR negative; or
	Molecular subtype luminal B (HER-2 negative); or
	Age under 35 years old; or yet
	1 to 3 affected lymph nodes if ER and PR positive.
High risk	4 or more positive lymph nodes; or
	Lymph nodes negative with ER. PR and HER-2 negative. pT higher than 2 cm; or
	Lymph node negative. pT higher than 1 cm and HER-2 positive.

pT: tumor size; ER: estrogen receptor; PR: progesterone receptor; HER-2: human epidermal growth factor receptor 2.