Table 4.

TGF-β1 and CTLA-4 expression profile in tumor tissue and immunological infiltrate from tumor biopsies.

Marker	INE	IE	p Value Δ
TGF-β1 tumor a	70%	80%	NS
TGF-β1 infiltrate a	40%	90%	<0.001 *
CTLA-4 tumor a	40%	10%	<0.001 *
CTLA-4 infiltrate a	70%	100%	<0.002 *
CD4 infiltrate b	50%	60%	NS
CD8 infiltrate b	50%	30%	0.0059 *

* Indicates p < 0.05. NS: not significant (>0.05). ^a Any positive labeling. ^b Positive labeling in at least 25% of observed lymphocytes. ^Δ Fisher’s exact test.