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Exosomal ncRNAs and lung cancer. Malignant cells produce exosomes that transport ncRNAs that can promote tumor growth to distant organs and the cancer microenvironment. ncRNAs can have a variety of impacts on recipient cells, including: (1) Increase cancer proliferation (2) Increase cancer drug resistance; (3) Modify immune cell signaling, affecting, and changing the immune response; (4) Alter the metabolism of cancer cells. Figure is created with BioRender.
