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. 2022 Nov 1;27(21):7437. doi: 10.3390/molecules27217437

Scheme 3.

Scheme 3

Reagents and conditions: (a) KOH, MeOH/H2O (12: 98%; 13: 96%); (b) N-(prop-2-yn-1-yl)hydroxylamine hydrochloride, HATU, DIPEA, DMF (4: 28%; 5: 30%).

HHS Vulnerability Disclosure