Figure 1.

L-cit alleviates mouse thymus damage and inhibits the iron deposition and LDH activity. Mice were intraperitoneally injected with iron dextran 50 mg/kg, and L-cit was given by gavage administration with a dosage of 0.5, 1.0, and 2.0 g/kg/day. (A) HE staining of thymus (C represents the thymic cortex, M represents thymus medulla). (B) Prussian blue staining of thymus (the arrow indicates iron deposition). (C) Iron concentration in serum. (D) LDH activity in serum. Values represent mean ± SEM. of three independent experiments. Significant differences are represented by * p < 0.05, ** p < 0.01, ns (not significant).