Table 4.
Diagnostic accuracy measurements of the TBS, and of LS-BMD calculated in the entire sample of the 992 women in the study (cutoff values = 1.204 for the TBS, and 0.800 g/cm2 for LS-BMD) and their comparison. The pre-test fracture prevalence was 8.67% (95% CI: 6.99–10.60).
| TBS Diagnostic Accuracy Values |
LS-BMD Diagnostic Accuracy Values |
p-Value TBS vs. LS-BMD |
|
|---|---|---|---|
| SE% (95% CI) | 72.09 (61.38–81.23) | 67.44 (56.48–77.16) | ns ( = 0.446) |
| SP% (95% CI) | 54.97 (51.66–58.24) | 58.06 (54.77–61.30) | 0.09 ( = 2.788) |
| PPV% (95% CI) | 13.19 (11.48–14.91) | 13.24 (11.34–15.15) | ns (TVpp WGS = 0.001) |
| NPV% (95% CI) | 95.40 (93.63–96.70) | 94.95 (93.24–96.24) | ns (TVpn WGS = 0.16) |
| OR (95% CI) | 3.15 (1.93–5.14) | 2.87 (1.79–4.59) | ns |
Legend: LS-BMD, lumbar spine bone mineral density; NPV, negative predictive value; ns, non-significant; OR, odds ratio; PPV, positive predictive value; SE, sensitivity; SP, specificity; TBS, trabecular bone score. Confidence intervals for SE, SP, and accuracy are “exact” Clopper–Pearson confidence intervals. Confidence intervals for the PPVs and the NPVs are Wald-type intervals.